F-Box Protein 31 (FBXO31) (Middle Region) Peptid
FBXO31
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN976747
Kurzübersicht für F-Box Protein 31 (FBXO31) (Middle Region) Peptid (ABIN976747)
Target
FBXO31
(F-Box Protein 31 (FBXO31))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FBXO31 Antibody(ARP53775_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXO31 (F-Box Protein 31 (FBXO31))
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Hintergrund
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FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CUL1,RBX1,SKP1
Protein Size: 367 -
Molekulargewicht
- 40 kDa
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Gen-ID
- 79791
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NCBI Accession
- NM_024735, NP_079011
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UniProt
- Q5XUX0
Target
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